A complex operation is described across four layers: the business it runs, the data it holds, the applications that process that data, and the technology that hosts them. A hospital is not only its patient-records system; it is also its clinical processes, its information, and its infrastructure together.
The frequent error is to reduce the enterprise to its software, so changing the systems is treated as the same as changing the enterprise itself. The better practice is to describe any change across all four domains, so business intent, information, applications, and technology stay aligned instead of one layer quietly drifting away from the others.